OCS Lung

The only FDA approved device for both standard and expanded* criteria donor lungs for transplantation

Often referred to as a “Lung-in-a-Box”, the OCS Lung is a revolutionary system that preserves donor organs. 

The OCS acts as a miniature intensive care unit that keeps organs alive and healthy by maintaining them in a natural state that mimics the human body

so that organs can remain viable for transplant along the way to recipients.

The Benefits of OCS Lung


The OCS Lung is FDA approved for use with standard criteria donor lungs

Improved post-transplant outcomes compared to cold storage

~50% reduction of primary graft dysfunction (PGD) grade 3

Significantly expanded organ retrieval range while limiting ischemic time

Reduction of PGD3 with OCS

PGD3 in the first 72 hours is a severe form of acute lung injury that is a major cause of early morbidity and mortality encountered after lung transplantation. TransMedics OCS Lung significantly reduced PGD3 vs control group in the INSPIRE Trial.

Significant Reduction of PGD3 within 72 Hours


The OCS Lung is FDA approved for use with expanded* criteria donor lungs

87% successful usage of donor lungs on OCS that had been rejected for transplant by centers using cold storage

Over 91% patient survival 1 year post transplant

Declined Lungs
UNOS data showed donor lungs used for the OCS Lung EXPAND Trial had been declined for transplantation on average 35 times by other transplant centers before reaching an OCS transplant center.


20+ hours of cross-clamp time in a successful retrieval and transplant from Hawaii to North Carolina

*Expanded criteria is defined as donor lung pairs initially deemed unacceptable for procurement and transplantation based on limitations of cold static preservation.

Meet Lee Ann

See how Lee Ann is living her life after transplant for her idiopathic pulmonary fibrosis since receiving lungs preserved in the TransMedics OCS.

It’s like taking the donor lungs and putting them in a nice, cozy warm environment and taking care of them and nurturing them.

Meet Mike

Discover why he believes the OCS Lung played a pivotal role in his wife’s recovery from a lung transplant for her idiopathic pulmonary fibrosis.

How could you compare having the organ on ice over a long period of time versus treating it in the OCS Lung device that actually helps improve the tissue and is able to monitor the lung?

Meet Silvano

Learn about the role TransMedics OCS played in his successful transplant surgery for pulmonary fibrosis.

Time is everything. My surgery was very challenging, it lasted 11-hours. Without the OCS, I feel that I wouldn’t be here now.

Locate an OCS Lung Center Near you

The OCS Lung is FDA approved for use with standard and expanded* criteria donor lungs. The OCS Lung is CE marked and commercially available in Europe and Australia.

Massachusetts General Hospital

Main Campus
55 Fruit Street
Boston, MA 02114

(617) 726-2000

Houston Methodist Hospital

6565 Fannin St
Houston, TX 77030

(713) 790-3311

Johns Hopkins Hospital

1800 Orleans St
Baltimore, MD 21287

(410) 955-5000

University of Minnesota Medical Center

909 Fulton St. SE
Minneapolis, MN 55455

(612) 273-8383

University of CA San Francisco Med Center

505 Parnassus Ave
San Francisco, CA 94143

(415) 353-1664

Duke University Medical Center

10 Duke Medicine Circle
Durham, NC 27710

(919) 372-3345 

Temple University Hospital

3401 N Broad St
Philadelphia, PA 19140

(215) 707-2000 

St. Joseph's (Dignity Health)

350 W Thomas Rd
Phoenix, AZ 85013

(602) 406-3000

University of Virginia (UVA)

1215 Lee St
Charlottesville, VA 22903

(434) 924-0000

UCLA Medical Center

757 Westwood Plaza
Los Angeles, CA 90095

(310) 825-9111


9200 W Wisconsin Ave
Milwaukee, WI 53226

(414) 805-3000

Stanford Medical Center

300 Pasteur Drive
Stanford, CA 94305 

(650) 498-7878

Tampa General Hospital

1 Tampa General Circle
Tampa, FL 33606
(800) 505-7769

Henry Ford Hospital

2799 West Grand Blvd.
Detroit, MI 48202
(855) 858-7267

University of Chicago Medicine

5841 S. Maryland Avenue
Chicago, IL 60637
(800) 824-2282

University of Nebraska Medical Center

983285 Nebraska Medical Center
Omaha, NE 68198
(800) 401-4444

Baylor St. Luke’s Medical Center

6770 Bertner Ave.
Houston, Texas 77030
(832) 355-3000

Montefiore Medical Center

111 E 210th St 2nd Floor
The Bronx, NY 10467
(718) 920-2800

Houston Methodist Hospital

6565 Fannin Street
Houston, TX 77030
(713) 790-3311

Hannover Medical School (Medizinische Hochschule Hannover)

Carl-Neuberg-Straße 1, 30625 Hannover, Germany

Royal Papworth Hospital, Cambridge, UK

Papworth Rd, Cambridge CB2 0AY, United Kingdom

Padua University Hospital, Padua, Italy

Via Nicolò Giustiniani, 2, 35128 Padova PD, Italy

Policlinico Le Scotte Siena, Siena, Italy

Viale Mario Bracci, 16, 53100 Siena SI, Italy

Ospedale Niguarda, Milan, Italy

Piazza dell'Ospedale Maggiore, 3, 20161 Milano MI, Italy

Hôpital Nord, Marseille, France

278 Rue Saint-Pierre, 13005 Marseille, France

National Research Cardiac Surgery Center, Astana, Kazakhstan

Turan Ave 38, Nur-Sultan 020000, Kazakhstan

Hopitaux Universitaires de Strasbourg, France

1 Place de L Hôpital, 67000 Strasbourg, France

University Hospital Gasthuisberg, Leuven, Belgium

3001 Leuven, Belgium

The OCS Lung, OCS Heart and OCS Liver are all CE marked devices. The OCS Lung is an FDA approved device for standard and expanded1 criteria donor lungs. The OCS Heart is an FDA approved device for expanded2 criteria donor hearts. The OCS Liver is an FDA approved device for DCD3 and DBD donor Livers.

1. Expanded criteria lungs is defined as donor lung pairs initially deemed unacceptable for procurement and transplantation based on limitations of cold static preservation.
2. Expanded criteria hearts is defined as donor hearts that are deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of prolonged cold static cardioplegic preservation (e.g., > 4 hours of cross-clamp time).
3. DCD livers < 55 years old with < 30 mins warm ischemia time and macrosteatosis < 15%.
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