OCS™ Heart

The only FDA approved technology for extracorporeal perfusion and preservation of donor hearts in the U.S.

The OCS Heart is a portable, warm perfusion, and monitoring system designed to keep a donor heart at a human-like, metabolically active state. By monitoring key parameters of the functioning heart, physicians may use their medical judgement to assess a potentially suitable heart’s condition and viability.

OCS DCD Heart Trial Results1

In this trial, risk-adjusted survival at 6 months after transplantation with a donor heart that had been reanimated and assessed with the use of extracorporeal nonischemic perfusion after circulatory death was clinically comparable to that after standard-care transplantation with a donor heart that had been preserved with the use of cold storage after brain death.

1Transplantation Outcomes with Donor Hearts after Circulatory Death

J.N. Schroder, C.B. Patel, A.D. DeVore, B.S. Bryner, S. Casalinova, A. Shah, J.W. Smith, A.G. Fiedler, M. Daneshmand, S. Silvestry, A. Geirsson, V. Pretorius, D.L. Joyce, J.Y. Um, F. Esmailian, K. Takeda, K. Mudy, Y. Shudo, C.T. Salerno, S.M. Pham, D.J. Goldstein, J. Philpott, J. Dunning, L. Lozonschi, G.S. Couper, H.R. Mallidi, M.M. Givertz, D.T. Pham, A.W. Shaffer, M. Kai, M.A. Quader, T. Absi, T.S. Attia, B. Shukrallah, B.C. Sun, M. Farr, M.R. Mehra, J.C. Madsen, C.A. Milano, and D.A. D’Alessandro

N Engl J Med 2023; 388:2121-2131DOI: 10.1056/NEJMoa2212438

OCS DCD offer similar outcomes as standard DBD heart transplants

Total 1,200+ U.S. DBD & DCD Heart Transplants

Data on file as of 3/2024

OCS™ Heart is the only system used and approved for DCD heart transplantation worldwide

OCS Heart EXPAND & Continued Access Results

EXPAND criteria donor hearts were 3 times more likely to be unutilized compared to standard criteria donor hearts, yet OCS allowed

87%

of those hearts to be successfully transplanted with excellent patient survival to 2 years post-transplant and low rates of severe PGD

EXPAND heart donors included:

  • 50% – Expected ischemic time >4 hours
  • 9% – Older donors >55 years
  • 18% – LVH
  • 29% – 20 or more mins of down time
  • 23% – LVEF of 40-50%
  • 8% – Presence of coronary artery disease
  • 15% – Alcoholism
  • 46% – Donors with multiple criteria

Our National OCS™ Program (NOP) is transforming organ transplantation

Delivering donor organs from anywhere in the U.S. to your Transplant Center

Locate an NOP center near you

University of Alabama at Birmingham

1720 University Blvd
Birmingham, AL 35233

(205) 934-4011

The University of Alabama, University Medical Center

850 Peter Bryce Boulevard
Tuscaloosa, AL 35401

(205) 348-1770

Baptist Health Medical Center-Little Rock

9601 Baptist Health Dr
Little Rock, AR 72205

(501) 202-2000

Banner University Medical Center

1111 E McDowell Rd., 2nd Floor
Phoenix, AZ 85006

(602) 839-9300

Mayo Clinic

5777 E Mayo Blvd
Phoenix, AZ 85054

(480) 342-2000

St. Joseph's Hospital and Medical Center

350 W Thomas Rd
Phoenix, AZ 85013

(602) 406-3000

Mayo Clinic

13400 E Shea Blvd
Scottsdale, AZ 85259

(480) 301-8000

Cedars-Sinai Medical Center

127 S San Vicente Blvd #A6100
Los Angeles, CA 90048

(310) 423-5460

Scripps Green Hospital

9888 Genesee Ave
San Diego, CA 92037

(858) 834-1798

California Pacific Medical Center

3773 Sacramento St
San Fransisco, CA 94110

(415) 600-6000

Loma Linda University Medical Center

11234 Anderson St
Loma Linda, CA 92354

(909) 558-4000

UCSF Medical Center at Mission Bay

1975 4th St
San Francisco, CA 94158

(415) 353-3000

Lucile Packard Children's Hospital Stanford

725 Welch Rd
Palo Alto, CA 94304

(650) 497-8000

California Pacific Medical Center

1101 Van Ness Ave
San Francisco, CA 94109

(415) 600-6000

University of California San Diego Medical Center

9300 Campus Point Drive
La Jolla, CA 92037

(619) 543-6222

University of CA San Francisco Med Center

505 Parnassus Ave
San Francisco, CA 94143

(415) 353-1664

UC Davis Medical Center

4301 X St
Sacramento, CA 95817

(916) 734-2011

Stanford Medical Center

300 Pasteur Drive
Palo Alto, CA 94304

(650) 723-8561

Ronald Reagan UCLA Medical Center

757 Westwood Plaza
Los Angeles, CA 90095

(310) 825-9111

Keck Medicine of USC - Keck Hospital of USC

1500 San Pablo St
Los Angeles, CA 90033

(800) 872-2273

Jacobs Medical Center at UC San Diego Health

9300 Campus Point Dr
San Diego, CA 92037

(858) 657-7000

Lifesharing Donate Life Organization

7436 Mission Valley Rd
San Diego, CA 92108

(619) 543-7225

Lucile Salter Packard Children's Hospital

401 Quarry Rd
Palo Alto, CA 94304

(650) 723-5511

Sharp Memorial Hospital

7901 Frost St.
San Diego, CA 92123

(858) 939-3400

University of California, San Diego

9300 Campus Pt. Dr
San Diego, CA 92103

(858) 657-7000

University of Colorado Health Science Center

13001 E 17th Pl
Aurora, CO 80045

(303) 724-5000

UCHealth University of Colorado Hospital

12605 E 16th Ave
Aurora, CO 80045

(720) 848-0000

Hartford Hospital

80 Seymour St
Hartford, CT 06106

(860) 545-5000

Yale New Haven Transplant Center

800 Howard Ave
New Haven, CT 06510

(203) 785-2565

Hartford HealthCare Heart & Vascular Institute

100 Retreat Ave STE 811
Hartford, CT 06106

(860) 522-5712

MedStar Washington Hospital Center

110 Irving St NW
Washington, DC 20010

(202) 877-7000

Nemours Children's Hospital

1600 Rockland R
Wilmington, DE 19803

(302) 651-4200

Weston Hospital | Cleveland Clinic Florida

2950 Cleveland Clinic Blvd
Weston, FL 33331

(954) 659-5000

AdventHealth Medical Group Transplant Institute

2415 N Orange Ave Suite 700
Orlando, FL 32803

(407) 303-2474

Joe DiMaggio Children's Hospital Foundation

3329 Johnson St
Hollywood, FL 33021

(954) 265-3454

Memorial Regional Hospital

3501 Johnson St
Hollywood, FL 33021

(954) 987-2000

Mayo Clinic

4500 San Pablo Road
Jacksonville, FL 32224

(904) 956-3309

HCA Florida Largo Hospital

201 14th St SW
Largo, FL 33770

(727) 588-5200

UF Health Shands Hospital

1600 SW Archer Rd
Gainesville, FL 32608

(352) 265-0111

Emory University Hospital

1365 Clifton Road Northeast, Building B
Atlanta, GA 30322

(855) 366-7989

Loyola University Medical Center

2160 S 1st Ave
Maywood, IL 60153

(888) 584-7888

Northwestern Medicine Organ Transplant Center

676 N St Clair St 19th Floor, Suite 1900
Chicago, IL 60611

(312) 695-8900

Rush University Medical Center

1653 W Congress Pkwy
Chicago, IL 60612

(312) 947-0100

The University of Chicago Department of Medicine

5841 S Maryland Ave
Chicago, IL 60637

(773) 702-1234

UK HealthCare - University of Kentucky

800 Rose St. First Floor, Suite G100
Lexington, KY 40536

(800) 456-5287

Beth Israel Deaconess Medical Center

110 Francis St
Boston, MA 02215

(617) 632-1070

Boston Children's Hospital

300 Longwood Ave
Boston, MA 02215

(617) 355-6000

Lahey Hospital & Medical Center

41 Burlington Mall Road
Burlington, MA 01805

(781) 744-5100

Massachusetts General Hospital

Main Campus
55 Fruit Street
Boston, MA 02114

(617) 726-2000

Tufts Medical Center

800 Washington St.
Boston, MA 02111

(617) 636-2273

Brigham and Women's Hospital

75 Francis St
Boston, MA 02115

(617) 732-5500

UMass Memorial Medical Center

55 N Lake Ave
Worcester, MA 01655

(508) 334-3452

University of Maryland Medical Center

22 S Greene St
Baltimore, MD 21201

(410) 328-8667

Corewell Health Butterworth Hospital

100 Michigan St NE
Grand Rapids, MI 49503

(616) 391-1774

Henry Ford Jackson Hospital

205 N East Ave
Jackson, MI 49201

(517) 205-4800

Cornell Health William Beaumont University Hospital

3601 W 13 Mile Rd
Royal Oak, MI 48073

(248) 898-5000

Henry Ford Hospital

2799 W Grand Blvd
Detroit, MI 48202

(313) 916-2600

Gift of Life Michigan Recovery Suite

3861 Research Park Dr
Ann Arbor, MI 48108

(866) 500-5801

Spectrum Health Hospitals

330 Barclay Ave NE
Grand Rapids, MI 49503

(866) 989-7999

University of Michigan Hospital

1500 E Medical Center Dr
Ann Arbor, MI 48109

(734) 936-4000

Mayo Clinic Hospital, Methodist Campus

201 W Center St
Rochester, MN 55902

(507) 266-7890

Abbott Northwestern Hospital

800 E 28th St
Minneapolis, MN 55407

(612) 863-3900

Mayo Clinic

200 1st St SW
Rochester, MN 55905

(800) 422-6296

University of Minnesota Medical Center

909 Fulton St. SE
Minneapolis, MN 55455

(612) 273-8383

St. Louis University Hospital

1201 S Grand Blvd
St. Louis, MO 63104

(314) 257-8000

University of Mississippi Medical Center

2500 N State St
Jackson, MS 39216

(601) 984-1000

Atrium Health Transplant Center

1025 Morehead Medical Drive Suite 600
Charlotte, NC 28203

(800) 562-5752

Duke Heart Transplant Clinic, Duke University Medical Center

40 Duke Medicine Cir Clinic 2F/2G
Durham, NC 27710

(919) 681-1300

UNC Hospitals

101 Manning Dr
Chapel Hill, NC 27514

(984) 974-1000

UNC School of Medicine

321 S Columbia St
Chapel Hill, NC 27599

(919) 962-8335

WakeMed Raleigh Campus

3000 New Bern Ave
Raleigh, NC 27610

(919) 350-8000

The Nebraska Medical Center

42nd and Emile
Omaha, NE 68105

(402) 559-4000

Newark Beth Israel Medical Center

201 Lyons Ave
Newark, NJ 07112

(800) 843-2384

Brookdale University Hospital Medical Center

1 Brookdale Plaza
Brooklyn, NY 11212

(718) 240-5000

New York Columbia Presbyterian CUIMC/Milstein Hospital Building

177 Fort Washington Ave
New York, NY 10032

(212) 305-2500

North Shore University Hospital

300 Community Dr
Manhasset, NY 11030

(516) 562-0100

NewYork-Presbyterian / Weill Cornell Medical Center

525 E 68th St
New York, NY 10065

(212) 746-5454

New York – Presbyterian Hospital/Columbia

177 Fort Washington Ave
New York, NY 10032

(800) 227-2762

Langone Hospital Kimmel Pavilion

424 E 34th St
New York, NY 10016

(212) 263-7300

Westchester Medical Center

257 Lafayette Ave # 300
Valhalla, NY 10901

(845) 368-0330

The Lauder Family Cardiovascular Center of Mount Sinai Heart

1190 5th Ave
New York, NY 10029

(855) 674-3278

Donor Memorial Lifeline of Ohio

770 Kinnear Rd
Columbus, OH 43212

(614) 291-5667

Cleveland Clinic Transplant Center

9500 Euclid Ave
Cleveland, OH 44195

(216) 444-6996

Cincinnati Children's Hospital Medical Center

3333 Burnet Ave
Cincinnati, OH 45229

(513) 636-4200

The Christ Hospital

2139 Auburn Ave
Cincinnati, OH 45219

(513) 585-2000

University of Cincinnati Medical Center

3188 Bellevue Avenue
Cincinnati, OH 45219

(513) 584-1000

UH Cleveland Medical Center

11100 Euclid Ave
Cleveland, OH 44106

(216) 541-1758

INTEGRIS Health Baptist Medical Center

3300 Northwest Expy
Oklahoma City, OK 73112

(405) 949-3011

Providence St. Vincent Medical Center

9205 SW Barnes Rd
Portland, OR 97225

(503) 216-1234

Oregon Health & Science University

3181 SW Sam Jackson Park Rd
Portland, OR 97239

(503) 494-8311

Hospital of the University of Pennsylvania - Pavilion

1 Convention Ave
Philadelphia, PA 19104

(215) 662-4000

University of Pittsburgh Medical Center

3459 Fifth Ave
Pittsburgh, PA 15213

(877) 640-6746

Thomas Jefferson University Hospital - Jefferson Health

111 S 11th St
Philadelphia, PA 19107

(215) 955-6000

Pittsburgh VA Medical Center

4100 Allequippa St
Pittsburgh, PA 15240

(412) 822-2222

MUSC Health University Medical Center

171 Ashley Ave
Charleston, SC 29425

(843) 792-1414

Vanderbilt University Medical Center

1215 21st Ave S
Nashville, TN 37232

(615) 936-3500

Baylor Scott & White Medical Center - Plano

4700 Alliance Blvd
Plano, TX 75093

(469) 814-2000

Baylor Scott & White Medical Center — Temple

2401 S 31st St
Temple, TX 76508

(254) 724-2111

Baylor University Medical Center

3500 Gaston Ave
Dallas, TX 75246

(214) 820-0111

St. Luke's Health - Baylor St. Luke's Medical Center

1101 Bates Ave
Houston, TX 77030

(832) 355-1000

Memorial Hermann-Texas Medical Center

6411 Fannin St
Houston, TX 77030

(713) 704-4000

Methodist Heart and Lung Institute Lung Center

7726 Louis Pasteur Dr
San Antonio, TX 78229

(210) 575-9500

Methodist Hospital Stone Oak

1139 E Sonterra Blvd
San Antonio, TX 78258

(210) 638-2000

Baylor Scott & White All Saints Medical Center — Fort Worth

1400 8th Ave
Fort Worth, TX 76104

(817) 926-2544

University Hospital

4502 Medical Drive
MS 18-1
San Antonio, TX 78229

(210) 567-5777

Children's Medical Center Dallas

1935 Medical District D
Dallas, TX 75235

(214) 456-7000

Dell Children's Medical Center

4900 Mueller Blvd
Austin, TX 78723

(512) 324-0000

Medical City Dallas Hospital

7777 Forest Ln
Dallas, TX 75230

(972) 566-7000

Methodist Hospital Specialty and Transplant

8026 Floyd Curl Dr
San Antonio, TX 78229

(210) 575-8110

UT Southwestern Medical Center

5323 Harry Hines Blvd
Dallas, TX 75390

(214) 648-3111

Baylor University Medical Center - Roberts Hospital

Scott & White Health 3500 Gaston Ave
Dallas, TX 75246

(214) 820-0111

William P. Clements Jr. University Hospital

6201 Harry Hines Blvd
Dallas, TX 75235

(214) 633-5555

Intermountain Medical Center

5121 Cottonwood St.
Murray, UT 84107

(801) 507-7000

University of Utah Hospital

50 Medical Dr N
Salt Lake City, UT 84132

(801) 581-2121

DonorConnect

6065 S Fashion Blvd #125
Murray, UT 84107

(801) 521-1755

Inova Fairfax Medical Campus

3300 Gallows Rd
Falls Church, VA 22042

(703) 776-4001

VCU Medical Center

1200 E Marshall St
Richmond, VA 23219

(804) 828-9000

VCU Health Hume-Lee Transplant Center

1200 E Marshall St 7th Floor
Richmond, VA 23219

(804) 828-4104

LifeCenter Northwest

3650 131st Ave SE
Bellevue, WA 98006

(877) 275-5269

UW Medical Center - Montlake

9725 3rd Ave NE #400
Seattle, WA 98195

(206) 598-3300

UW Medical Center - Northwest

1550 N 115th St Main Hospital
Seattle, WA 98133

(877) 694-4677

University of Washington School of Medicine

1959 NE Pacific St
Seattle, WA 98195

(206) 543-2100

Froedtert Luth Memorial Hospital

9200 W. Wisconsin Ave
Milwaukee, WI 53226

(414) 777-7700

Aurora St Luke's Medical Center

2900 W Oklahoma Ave
Milwaukee, WI 53215

(414) 649-6000

The OCS Lung, OCS Heart and OCS Liver are all CE marked devices. The OCS Lung is an FDA approved device for standard and expanded1 criteria donor lungs. The OCS Heart is an FDA approved device for DCD and expanded2 criteria donor hearts. The OCS Liver is an FDA approved device for DCD3 and DBD donor Livers.
1. Expanded criteria lungs is defined as donor lung pairs initially deemed unacceptable for procurement and transplantation based on limitations of cold static preservation.
2. Expanded criteria hearts is defined as donor hearts that are deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of prolonged cold static cardioplegic preservation (e.g., > 4 hours of cross-clamp time).
3. DCD livers < 55 years old with < 30 mins warm ischemia time and macrosteatosis < 15%.

Only multi-organ platform used with donor lungs, hearts and livers

Largest user base at more than 70 leading US and global transplant centers

Largest body of literature and clinical evidence in warm perfusion

Most extensive training program including 24/7 clinical support

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