OCS™ Heart
The only FDA approved technology for extracorporeal perfusion and preservation of donor hearts in the U.S.
The OCS Heart is a portable, warm perfusion, and monitoring system designed to keep a donor heart at a human-like, metabolically active state. By monitoring key parameters of the functioning heart, physicians may use their medical judgement to assess a potentially suitable heart’s condition and viability.
OCS Heart EXPAND Clinical Trial Results
U.S. pivotal trial to evaluate the Organ Care System for use with unutilized donor hearts that may not meet current standard acceptance criteria for transplantation.
270+ DCD Heart Transplants
OCS™ Heart is the only system used in DCD heart transplantation worldwide
With 75 patients enrolled, the following types of expanded criteria donor hearts were used:
- 37% – Expected ischemic time >4 hours
- 31% – 20 or more mins of down time
- 28% – LVEF of 40-50%
- 13% – Older donors >55 years
- 8% – Coronary artery disease
- (31 Patients had 2 or more indications)
Primary Effectiveness Endpoints
UNOS data showed donor hearts used for the OCS Heart EXPAND Trial had been declined for transplantation on average 66 times by other transplant centers before reaching an OCS transplant center.
Patient Survival
Absence of severe primary heart graft dysfunction (PGD) in the first 24 hours post-transplantation
Want to learn more about the benefits of OCS?
Locate an OCS Heart Center Near You
The OCS Heart is FDA approved. The OCS Heart is CE marked and commercially available in Europe, Australia, Canada, Middle East and Asia.
Massachusetts General Hospital
Main Campus
55 Fruit Street
Boston, MA 02114
(617) 726-2000
Houston Methodist Hospital
6565 Fannin St
Houston, TX 77030
Henry Ford Hospital
2799 W Grand Blvd
Detroit, MI 48202
UT Southwestern Medical Center
5323 Harry Hines Blvd
Dallas, TX 75390
Emory University Hospital
1365 Clifton Road Northeast, Building B
Atlanta, GA 30322
(855) 366-7989
University of Minnesota Medical Center
909 Fulton St. SE
Minneapolis, MN 55455
(612) 273-8383
University of Washington Medical Center
9725 3rd Ave NE #400
Seattle, WA 98115
(206) 598-3300
University of CA San Francisco Medical Center
505 Parnassus Ave
San Francisco, CA 94143
(415) 353-1664
Scripps Green Hospital
10666 N. Torrey Pines Rd.
La Jolla, CA 92037
(858) 554-9100
University Hospital
4502 Medical Drive
MS 18-1
San Antonio, TX
78229
(210) 567-5777
Tampa General Hospital
1 Tampa General Circle
Tampa, FL 33606
(800) 505-7769
Montefiore Medical Center
111 East 210 Street
Bronx, NY 10467
718-920-4321
Mount Sinai Medical Center
1 Gustave Levy Place
New York, NY 10029
212-241-6500
The Nebraska Medical Center
42nd and Emile
Omaha, NE 68198
402-559-4000
University of California San Diego Medical Center
9300 Campus Point Drive
San Diego, CA 92037
619-543-6222
Stanford Hospital
300 Pasteur Drive
Stanford, CA 94305
(650) 723-5771
Duke Heart Transplant Clinic
40 Duke Medicine Cir Clinic 2F/2G
Durham, NC 27710
(919) 681-1300
Yale New Haven Transplant Center
800 Howard Ave
New Haven, CT 06519
(203) 785-2565
Vanderbilt University Medical Center
1215 21st Ave S
Nashville, TN 37232
(615) 936-3500
Mayo Clinic
200 1st St SW
Rochester, MN 55905
(800) 422-6296
Mayo Clinic
4500 San Pablo Road
Jacksonville, FL 32224
(904) 956-3309
Atrium Health Transplant Center
1025 Morehead Medical Drive Suite 600
Charlotte, NC 28204
(800) 562-5752
Cedars-Sinai Medical Center
127 S San Vicente Blvd #A6100
Los Angeles, CA 90048
(310) 423-5460
New York – Presbyterian Hospital/Columbia
177 Fort Washington Ave
New York, NY 10032
(800) 227-2762
Westchester Medical Center
257 Lafayette Ave # 300
Suffern, NY 10901
(845) 368-0330
University of Pittsburgh Medical Center
3459 Fifth Ave
Pittsburgh, PA 15213
(877) 640-6746
Baylor University Medical Center, part of Baylor Scott & White Health
3500 Gaston Ave
Dallas TX 75246
(214) 820-0111
Tufts Medical Center
800 Washington St.
Boston, MA 02111
(617) 636-2273
UK HealthCare - University of Kentucky
800 Rose St. First Floor, Suite G100
Lexington, KY 40536
(800) 456-5287
Minneapolis Heart Institute
800 E 28th St
Minneapolis, MN 55407
(612) 863-3900
University of Michigan Hospital
1500 E Medical Center Dr
Ann Arbor, MI 48109
(734) 936-4000
Northwestern Medicine Organ Transplant Center
676 N St Clair St 19th Floor, Suite 1900
Chicago, IL 60611
(312) 695-8900
MUSC Health University Medical Center
171 Ashley Ave
Charleston, SC 29425
(843) 792-1414
Lucile Packard Children's Hospital
725 Welch Rd
Palo Alto, CA 94304
(650) 497-8000
Cincinnati Children's Hospital Medical Center
3333 Burnet Ave
Cincinnati OH 45229
(513) 636-4200
Brigham and Women's Hospital
75 Francis St
Boston, MA 02115
(617) 732-5500
AdventHealth Medical Group Transplant Institute
2415 N Orange Ave Suite 700
Orlando, FL 32804
(407) 303-2474
Providence St. Vincent Medical Center
9205 SW Barnes Rd
Portland, OR 97225
(503) 216-1234
Mayo Clinic
5777 E Mayo Blvd
Phoenix, AZ 85054
(480) 342-2000
The University of Chicago Department of Medicine
5841 S Maryland Ave
Chicago, IL 60637
(773) 702-1234
Froedtert Hospital MCW
9200 W. Wisconsin Ave
Milwaukee, WI 53226
(414) 777-7700
Sharp Memorial Hospital
7901 Frost St.
San Diego, CA 92123
(858) 939-3400
Cleveland Clinic Transplant Center
9500 Euclid Ave
Cleveland, OH 44195
(216) 444-6996
UC Medical Center
3188 Bellevue Avenue
Cincinnati, OH 45219
(513) 584-1000
Aurora St Luke's Medical Center
2900 W Oklahoma Ave
Milwaukee, WI 53215
(414) 649-6000
Hartford Hospital
80 Seymour St
Hartford, CT 06106
(860) 545-5000
UNC Hospitals
101 Manning Dr
Chapel Hill, NC 27514
(984) 974-1000
Ronald Reagan UCLA Medical Center
757 Westwood Plaza
Los Angeles, CA 90095
(310) 825-9111
MISH - Spectrum Health Hospitals
330 Barclay Ave NE
Grand Rapids MI 49503
(866) 989-7999
California Pacific Medical Center
3773 Sacramento St
San Francisco, CA 94118
(415) 600-6000
Newark Beth Israel Medical Center
201 Lyons Ave
Newark, NJ 07112
(800) 843-2384
The OCS Lung, OCS Heart and OCS Liver are all CE marked devices. The OCS Lung is an FDA approved device for standard and expanded1 criteria donor lungs. The OCS Heart is an FDA approved device for expanded2 criteria donor hearts. The OCS Liver is an FDA approved device for DCD3 and DBD donor Livers.
1. Expanded criteria lungs is defined as donor lung pairs initially deemed unacceptable for procurement and transplantation based on limitations of cold static preservation.
2. Expanded criteria hearts is defined as donor hearts that are deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of prolonged cold static cardioplegic preservation (e.g., > 4 hours of cross-clamp time).
3. DCD livers < 55 years old with < 30 mins warm ischemia time and macrosteatosis < 15%.
Only multi-organ platform used with donor lungs, hearts and livers
Largest user base at 70 leading US and global transplant centers
Largest body of literature and clinical evidence in warm perfusion
Most extensive training program including 24/7 clinical support