OCS™ Heart

The only FDA approved technology for extracorporeal perfusion and preservation of donor hearts in the U.S.

The OCS Heart is a portable, warm perfusion, and monitoring system designed to keep a donor heart at a human-like, metabolically active state. By monitoring key parameters of the functioning heart, physicians may use their medical judgement to assess a potentially suitable heart’s condition and viability.

OCS Heart EXPAND Clinical Trial Results

U.S. pivotal trial to evaluate the Organ Care System for use with unutilized donor hearts that may not meet current standard acceptance criteria for transplantation.

270+ DCD Heart Transplants

OCS™ Heart is the only system used in DCD heart transplantation worldwide

With 75 patients enrolled, the following types of expanded criteria donor hearts were used:

  • 37% Expected ischemic time >4 hours
  • 31% 20 or more mins of down time
  • 28% LVEF of 40-50%
  • 13% Older donors >55 years
  • 8% Coronary artery disease
  • (31 Patients had 2 or more indications)
Primary Effectiveness Endpoints
OCS Heart has shown a significant reduction of injurious ischemic time compared to cold storage

UNOS data showed donor hearts used for the OCS Heart EXPAND Trial had been declined for transplantation on average 66 times by other transplant centers before reaching an OCS transplant center.

Patient Survival

OCS Lung has shown an approximate 50% reduction of primary graft dysfunction (PGD) grade 3*

Absence of severe primary heart graft dysfunction (PGD) in the first 24 hours post-transplantation

Want to learn more about the benefits of OCS?

Locate an OCS Heart Center Near You

The OCS Heart is FDA approved. The OCS Heart is CE marked and commercially available in Europe, Australia, Canada, Middle East and Asia.

Massachusetts General Hospital

Main Campus
55 Fruit Street
Boston, MA 02114

(617) 726-2000

Houston Methodist Hospital

6565 Fannin St
Houston, TX 77030

(713) 790-3311

Henry Ford Hospital

2799 W Grand Blvd
Detroit, MI 48202

(313) 916-2600

UT Southwestern Medical Center

5323 Harry Hines Blvd
Dallas, TX 75390

(214) 648-3111

University of Virginia HSC

1189-1221 Lee St
Charlottesville, VA 22903

(800) 251-3627

MCV Hospitals

1250 East Marshall Street 
Richmond, VA 23298

(804) 828-4104

Emory University Hospital

1365 Clifton Road Northeast, Building B
Atlanta, GA 30322
(855) 366-7989

Johns Hopkins Hospital

1800 Orleans St
Baltimore, MD 21287

(410) 955-5000

University of Minnesota Medical Center

909 Fulton St. SE
Minneapolis, MN 55455

(612) 273-8383

University of Washington Medical Center

9725 3rd Ave NE #400
Seattle, WA 98115

(206) 598-3300

University of CA San Francisco Medical Center

505 Parnassus Ave
San Francisco, CA 94143

(415) 353-1664

Ohio State University Medical Center

410 W 10th Ave
Columbus, OH 43210

(614) 293-8000

Scripps Green Hospital

10666 N. Torrey Pines Rd.
La Jolla, CA 92037
(858) 554-9100

University Hospital

4502 Medical Drive
MS 18-1
San Antonio, TX
78229
(210) 567-5777

Tampa General Hospital

1 Tampa General Circle
Tampa, FL 33606
(800) 505-7769

Methodist University Hospital

1265 Union Avenue
Memphis, TN 38104
901-516-9183

Montefiore Medical Center

111 East 210 Street
Bronx, NY 10467
718-920-4321

Mount Sinai Medical Center

1 Gustave Levy Place
New York, NY 10029
212-241-6500

The Nebraska Medical Center

42nd and Emile
Omaha, NE 68198
402-559-4000

University of California San Diego Medical Center

9300 Campus Point Drive
San Diego, CA 92037
619-543-6222

The OCS Lung, OCS Heart and OCS Liver are all CE marked devices. The OCS Lung is an FDA approved device for standard and expanded1 criteria donor lungs. The OCS Heart is an FDA approved device for expanded2 criteria donor hearts. The OCS Liver is an FDA approved device for DCD3 and DBD donor Livers.

1. Expanded criteria lungs is defined as donor lung pairs initially deemed unacceptable for procurement and transplantation based on limitations of cold static preservation.
2. Expanded criteria hearts is defined as donor hearts that are deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of prolonged cold static cardioplegic preservation (e.g., > 4 hours of cross-clamp time).
3. DCD livers < 55 years old with < 30 mins warm ischemia time and macrosteatosis < 15%.

Only multi-organ platform used with donor lungs, hearts and livers

Largest user base at 70 leading US and global transplant centers

Largest body of literature and clinical evidence in warm perfusion

Most extensive training program including 24/7 clinical support

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