OCS™ Lung

The only FDA approved device for both standard and expanded* criteria donor lungs for transplantation.

The OCS Lung is a portable perfusion, ventilation, and monitoring system that maintains the organ at a near-physiologic state – allowing physicians to assess and improve the condition of lungs between the donor and recipient sites.

*Expanded criteria is defined as donor lung pairs initially deemed unacceptable for procurement and transplantation based on limitations of cold static preservation.

The Benefits of OCS Lung

The only FDA approved device for both standard and expanded* criteria donor lungs for transplantation.

INSPIRE TRIAL RESULTS

OCS Heart has shown a significant reduction of injurious ischemic time compared to cold storage

Improved post-transplant outcomes compared to cold storage

Significantly expanded organ retrieval range while limiting ischemic time

~50% reduction of primary graft dysfunction (PGD) grade 3^†

Significant Reduction of PGD3 within 72 Hours

†PGD3 in the first 72 hours is a severe form of acute lung injury that is a major cause of early morbidity and mortality encountered after lung transplantation. TransMedics OCS Lung significantly reduced PGD3 vs control group in the INSPIRE Trial.

EXPAND TRIAL RESULTS

87% successful usage of donor lungs on OCS that had been rejected for transplant by centers using cold storage

Over 91% patient survival 1-year post-transplant

Declined Lungs for transplantation on average 35 times* by other transplant centers

*UNOS data showed donor lungs used for the OCS Lung EXPAND Trial had been declined for transplantation on average 35 times by other transplant centers before reaching an OCS transplant center.

Long-distance retrieval

20+ hours of cross-clamp time in a successful retrieval and transplant from Hawaii to North Carolina

See how Lee Ann is living her life after transplant for her idiopathic pulmonary fibrosis.

It’s like taking the donor lungs and putting them in a nice, cozy warm environment and taking care of them and nurturing them.”

-Lee Ann, OCS Lung patient

Watch her video

Discover why Mike believes the OCS Lung played a pivotal role in his wife’s recovery from a lung transplant for her idiopathic pulmonary fibrosis.

How could you compare having the organ on ice over a long period of time versus treating it in the OCS Lung device that actually helps improve the tissue and is able to monitor the lung?”

-Mike, relative of OCS Lung patient

Watch his video

Learn about the role TransMedics OCS played in Silvano’s successful transplant surgery for pulmonary fibrosis.

Time is everything. My surgery was very challenging, it lasted 11-hours. Without the OCS, I feel that I wouldn’t be here now.”

-Silvano, OCS Lung patient

Watch his video

Locate an OCS Lung Center Near You

The OCS Lung is FDA approved for use with standard and expanded* criteria donor lungs. The OCS Lung is CE marked and commercially available in Europe and Australia.

Massachusetts General Hospital

Main Campus
55 Fruit Street
Boston, MA 02114

(617) 726-2000

Houston Methodist Hospital

6565 Fannin St
Houston, TX 77030

(713) 790-3311

Johns Hopkins Hospital

1800 Orleans St
Baltimore, MD 21287

(410) 955-5000

University of Minnesota Medical Center

909 Fulton St. SE
Minneapolis, MN 55455

(612) 273-8383

University of CA San Francisco Med Center

505 Parnassus Ave
San Francisco, CA 94143

(415) 353-1664

Duke University Medical Center

10 Duke Medicine Circle
Durham, NC 27710

(919) 372-3345

Temple University Hospital

3401 N Broad St
Philadelphia, PA 19140

(215) 707-2000

St. Joseph's (Dignity Health)

350 W Thomas Rd
Phoenix, AZ 85013

(602) 406-3000

University of Virginia (UVA)

1215 Lee St
Charlottesville, VA 22903

(434) 924-0000

UCLA Medical Center

757 Westwood Plaza
Los Angeles, CA 90095

(310) 825-9111

MCW/Froedtert

9200 W Wisconsin Ave
Milwaukee, WI 53226

(414) 805-3000

Stanford Medical Center

300 Pasteur Drive
Stanford, CA 94305

(650) 498-7878

Tampa General Hospital

1 Tampa General Circle
Tampa, FL 33606
(800) 505-7769

Henry Ford Hospital

2799 West Grand Blvd.
Detroit, MI 48202
(855) 858-7267

University of Chicago Medicine

5841 S. Maryland Avenue
Chicago, IL 60637
(800) 824-2282

University of Nebraska Medical Center

983285 Nebraska Medical Center
Omaha, NE 68198
(800) 401-4444

Baylor St. Luke’s Medical Center

6770 Bertner Ave.
Houston, Texas 77030
(832) 355-3000

Montefiore Medical Center

111 E 210th St 2nd Floor
The Bronx, NY 10467
(718) 920-2800

Houston Methodist Hospital

6565 Fannin Street
Houston, TX 77030
(713) 790-3311

Hannover Medical School (Medizinische Hochschule Hannover)

Carl-Neuberg-Straße 1, 30625 Hannover, Germany

Royal Papworth Hospital, Cambridge, UK

Papworth Rd, Cambridge CB2 0AY, United Kingdom

Padua University Hospital, Padua, Italy

Via Nicolò Giustiniani, 2, 35128 Padova PD, Italy

Policlinico Le Scotte Siena, Siena, Italy

Viale Mario Bracci, 16, 53100 Siena SI, Italy

Ospedale Niguarda, Milan, Italy

Piazza dell'Ospedale Maggiore, 3, 20161 Milano MI, Italy

Hôpital Nord, Marseille, France

278 Rue Saint-Pierre, 13005 Marseille, France

National Research Cardiac Surgery Center, Astana, Kazakhstan

Turan Ave 38, Nur-Sultan 020000, Kazakhstan

Hopitaux Universitaires de Strasbourg, France

1 Place de L Hôpital, 67000 Strasbourg, France

University Hospital Gasthuisberg, Leuven, Belgium

3001 Leuven, Belgium

The OCS Lung, OCS Heart and OCS Liver are all CE marked devices. The OCS Lung is an FDA approved device for standard and expanded1 criteria donor lungs. The OCS Heart is an FDA approved device for expanded2 criteria donor hearts. The OCS Liver is an FDA approved device for DCD3 and DBD donor Livers.

1. Expanded criteria lungs is defined as donor lung pairs initially deemed unacceptable for procurement and transplantation based on limitations of cold static preservation.

2. Expanded criteria hearts is defined as donor hearts that are deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of prolonged cold static cardioplegic preservation (e.g., > 4 hours of cross-clamp time).

OCS™ Lung

*Expanded criteria is defined as donor lung pairs initially deemed unacceptable for procurement and transplantation based on limitations of cold static preservation.

The Benefits of OCS Lung

INSPIRE TRIAL RESULTS

EXPAND TRIAL RESULTS

*UNOS data showed donor lungs used for the OCS Lung EXPAND Trial had been declined for transplantation on average 35 times by other transplant centers before reaching an OCS transplant center.

Want to learn more about the benefits of OCS, or access our OCS publications repository for additional insights?

Long-distance retrieval

See how Lee Ann is living her life after transplant for her idiopathic pulmonary fibrosis.

Discover why Mike believes the OCS Lung played a pivotal role in his wife’s recovery from a lung transplant for her idiopathic pulmonary fibrosis.

Learn about the role TransMedics OCS played in Silvano’s successful transplant surgery for pulmonary fibrosis.

Locate an OCS Lung Center Near You

Massachusetts General Hospital

Houston Methodist Hospital

Johns Hopkins Hospital

University of Minnesota Medical Center

University of CA San Francisco Med Center

Duke University Medical Center

Temple University Hospital

St. Joseph's (Dignity Health)

University of Virginia (UVA)

UCLA Medical Center

MCW/Froedtert

Stanford Medical Center

Tampa General Hospital

Henry Ford Hospital

University of Chicago Medicine

University of Nebraska Medical Center

Baylor St. Luke’s Medical Center

Montefiore Medical Center

Houston Methodist Hospital

Hannover Medical School (Medizinische Hochschule Hannover)

Royal Papworth Hospital, Cambridge, UK

Padua University Hospital, Padua, Italy

Policlinico Le Scotte Siena, Siena, Italy

Ospedale Niguarda, Milan, Italy

Hôpital Nord, Marseille, France

National Research Cardiac Surgery Center, Astana, Kazakhstan

Hopitaux Universitaires de Strasbourg, France

University Hospital Gasthuisberg, Leuven, Belgium

1. Expanded criteria lungs is defined as donor lung pairs initially deemed unacceptable for procurement and transplantation based on limitations of cold static preservation.

2. Expanded criteria hearts is defined as donor hearts that are deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of prolonged cold static cardioplegic preservation (e.g., > 4 hours of cross-clamp time).

3. DCD livers < 55 years old with < 30 mins warm ischemia time and macrosteatosis < 15%.