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Key Advantages

Organ Care System

What are the Benefits of the TransMedics Organ Care System?

Since the advent of transplantation, the cornerstone of organ preservation has been cold ischemic storage. Although this method was intended to help reduce the extent of organ damage during transport, significant damage still occurs. The more time that passes, the more damage occurs.

Living organ transplant performed with the TransMedics Organ Care System could resolve many of the limitations associated with cold ischemic storage. By pumping warm, oxygenated, nutrient-rich blood through the organ from the time of removal until it is implanted, the organ may withstand longer periods of time outside of the body and be less vulnerable to damage during transportation to the recipient. More extensive testing for function and tissue matching may also be possible with a functioning organ.

We have designed the Organ Care System to offer the following potential advantages over cold ischemic preservation:

  • Less time dependent ischemic inujury to donor organs
  • Ability to evaluate the functional status of donor organs outside the body
  • Ability to resuscitate organs after removal from the donor

In addition, by increasing the number of transplantable organs and decreasing the risk of post-transplant complications, this technology could potentially provide significant cost benefits to the healthcare system, including:

  • Improved patient outcomes
  • Increased utilization of available organs
  • Expansion of the pool of potential donors
  • Reduced total cost of care


US: Caution—Investigational Device. Limited by Federal law to investigational use.

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